SPPS · Statistical Packages for Pharmaceutical Sciences

Open computational tools for pharmaceutical technology

Dissolution kinetics, release-profile comparison, pseudo-ternary phase diagrams, dose–response and basic statistics: free tools that run in the browser and work directly with laboratory data.

The tools are web versions of desktop programs developed since 1995 at the Department of Pharmaceutical Technology, Faculty of Pharmacy, Ege University (İzmir, Türkiye). The kinetics engine is validated against DDSolver outputs, and the source code is open. Data you enter never leaves your browser session; nothing is stored on the server.

The Turkish edition is at spps.tr, the English edition at spps.tech. The guides are currently available in Turkish only; English versions are in preparation.

Featured tools

Kinetic Analysis Fits release data to Higuchi, Korsmeyer–Peppas, Weibull, Hopfenberg and twelve more models; ranks them by AIC. Open Ternary Phase Diagram Draws pseudo-ternary phase diagrams and measures the area and centroid of each region. Open f1 / f2 Test Compares two dissolution profiles with the difference (f1) and similarity (f2) factors. Open

Pharmaceutical Technology

Kinetic Analysis Fits release data to Higuchi, Korsmeyer–Peppas, Weibull and other models f1 / f2 Test Compares two dissolution profiles with the f1 and f2 factors t-Test Independent and paired-sample t-tests, with Levene's test for equal variances LD50 Calculator LD50/LD90 and confidence intervals from dose–response data by probit, logit and 4PL Ternary Phase Diagram Draws pseudo-ternary phase diagrams and shows the mixture regions

Guides

Kinetic Analysis Guide Models, fitting, criteria, a worked example, common mistakes and the Turkish school; 48 references (in Turkish) Ternary Phase Diagram Guide Reading the diagram, water titration, phase regions, area and centroid, terminology; 36 references (in Turkish)